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Created Jun 2019 | Updated Nov 2020




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Drostanolone Propionate is an anabolic androgenic steroid that first hit the market around 1970 under the trade name Masteron manufactured by Syntex. Syntex would also provide the compound under numerous other brand names such as Masteril and Metormon among others, as well as Drolban however, Masteron has remained the most recognizable brand. As a therapeutic agent, Masteron enjoyed two decades of success in combating advanced inoperable breast cancer in postmenopausal women. It would also become a popular cutting steroid among bodybuilders, which is where Masteron is currently most commonly found. However, the original Masteron brand is no longer available; in fact, nearly every pharmaceutical brand on earth has been discontinued. This compound is still approved by the U.S. FDA, but it is rarely used in breast cancer treatment any longer in favor of other options. The steroid is, however, still tremendously popular in competitive bodybuilding cycles and often considered essential to contest preparation.

On a functional basis, Masteron is well-known for being one of the only anabolic steroids with strong anti-estrogenic properties. Not only does this steroid carry no estrogenic activity, but it can actually act as an anti-estrogen in the body. This is why it has been effective in the treatment of breast cancer.

  • For those that are not competitive bodybuilder lean, it is possible that the effects of Masteron may not be all that noticeable. The individual who is under 10% body fat should be able to notice some results and produce a harder, dryer look, but much over 10% and the effects may not be all that pronounced.
  • As a potent androgen, Masteron can benefit the athlete looking for a boost in strength.
  • As a bulking agent, the effects of Masteron will prove to be rather week.
  • In many ways, Masteron is a fairly side effect friendly anabolic steroid.
  • An important note; the Drostanolone hormone is not metabolized by the 5-alpha reductase enzyme. This is the enzyme responsible for reducing testosterone to dihydrotestosterone. In the case of Masteron, it's already DHT; there is no reduction.
  • Masteron can have a significant effect on cholesterol. This can result in an increase in LDL cholesterol, as well as a decrease in HDL cholesterol with the strongest emphasis on the latter.
  • Masteron will significantly suppress natural testosterone production making exogenous testosterone therapy important when using this steroid.
  • Masteron is not a hepatotoxic anabolic androgenic steroid and will present no stress or damage to the liver.
The original Masteron brand of Drostanolone Propionate is no longer manufactured. Anyone purporting to have Syntex Masteron is providing a counterfeit product. Drostanolone in any form, and it is very scarce on the world market. However, this hormonal compound is widely available on the black market. The Mastabolin brand by Alpha Pharma should be in high supply in most markets.

Masteron (Drostanolone) is an anabolic steroid known as a cosmetic drug due to its strong DHT (dihydrotestosterone) properties. It is most popular among those who are competing or looking for a more aesthetic physique vs. those who are strength training. Today those doing physique competitions love using it because it is such a fantastic compound for hardening and drying of the muscles. It, along with other dry compounds like Winstrol, are considered two of the most used steroids ahead of any bodybuilding competition. Masteron (Drostanolone) is popular in a stack for those gym rats who do not like compounds that aromatize into estrogen. It is not used for those seeking to bulk or those who are struggling with appetite or weight.

Masteron (Drostanolone) has always come as an injectable oil with a propionate ester attached. Masteron (Drostanolone) is a straight DHT (dihydrotestosterone) derivative. This makes it more anabolic and more efficient at working in the body than the DHT we naturally produce. It also cannot aromatize into estrogen like other anabolic steroids such as Testosterone or Dianabol for example. Another awesome trait of Masteron (Drostanolone) is that it is very good at binding to SHBG (sex hormone binding globulin). When this happens you open up more free testosterone in the body, this will make the steroids you are already taking more effective. Like all steroids, it will increase protein synthesis. In addition, it helps boost red blood cell count to give you an advantage over your peers in the gym. All in all, when you use this steroid as part of your stack you will boost your entire steroid cycle, harden up your muscles, give yourself a dry look, and possibly even boost libido a bit.

Drostanolone propionate is described in product literature as a "steroid with powerful anabolic and anti-estrogenic properties," and indeed does seem to share some of both properties. Admittedly, however, its anabolic properties are more properly described as moderate, especially when placed in the context of other agents. The drug is most often used by dieting bodybuilders and athletes in speed sports, where it is highly favored for its ability to produce solid increases in lean muscle mass and strength, which are usually accompanied by reductions in body fat level and minimal side effects.

While highly popular among athletes during the 1970's and '80's, drostanolone propionate ultimately enjoyed limited success as a prescription agent. Manufacturers began voluntarily discontinuing sale of the agent in various markets before long, likely due to the advent of more effective therapies for breast cancer, as well as the slow decline in steroid prescriptions for this phase of treatment. One of the first preparations to go was the U.S. Drolban, which was removed from market during the late 1980's. Permastril and Metormon were soon dropped as well. The last remaining Western preparation containing drostanolone propionate was Masteron from Belgium, which disappeared by the late 1990's. Drostanolone propionate remains listed on the U.S. Pharmacopias, suggesting there is presently no legal roadblock to its sale, although its reemergence as a prescription drug product seems highly unlikely.

Drostanolone propionate was not FDA approved for use in men. Prescribing guidelines are unavailable. Drostanolone propionate is often combined with other steroids for an enhanced effect. Common stacks include an injectable anabolic such as Deca-Durabolin (nandrolone decanoate) or Equipoise (boldenone undecylenate). Drostanolone propionate is presently unavailable as a prescription drug product. There are limited supplies from export-oritented pharmaceutical companies, but the vast majority comes from underground steroid manufacturers. Following recent market trends, we find that black market preparations labeled as drostanolone propionate carry a moderate to high risk of containing no or substitute steroid ingredients.

after a long period of time as a rare drug is now enjoying greater popularity, and deservedly so. Where one does not wish to use a large amount of injectable testosterone and wishes to use either no trenbolone or only a modest amount of that drug, Masteron is often an ideal choice for inclusion in a steroid stack, or in some cases for use as the sole injectable for a steroid cycle. Masteron undergoes no aromatization (conversion to estrogen), no conversion to DHT or potentiation by the 5-AR enzyme, and as an unalkylated steroid it poses no liver issues. In these regards and also in overall side effects, Masteron is best compared with Primobolan Depot. Many have called Masteron a "weak" steroid, but this definitely is not the case. What often has been weak has been the doses! When included as part of a steroid stack, Masteron's contribution per milligram is at least as great as that of testosterone, boldenone (Equipoise), nandrolone (Deca), or methenolone (Primobolan). Very simply, Masteron does very well what it's supposed to do, and has as mild a side-effect profile as is possible for an anabolic steroid. I have never known anyone to be disappointed with this steroid, provided sufficient dosing was used.

Although its anabolic and androgenic strengths fall in the mild or low category, its androgenic properties are very visible, including hardening of the muscle and deepening of the voice. Masteron hardens muscles while keeping the fat or lipid content low in the body. Its cycle is short which means it lasts in the body for not more than 60 hours after consumption. This makes Masteron an effective "pre-contest" steroid. Also, its effects have been found to be most pronounced when administered on a body, which already has minimal fat and falls in the category of skinny. On contrary to what was popularly believed, it is not to be used by women other than for treatment. It has been observed over the years that its adrogenic properties are strong despite having a low strength. This is because being a DHT drug; it is five times more adrogenic than testosterone to which it is compared. To top it, it has shown a couple of times more affinity to receptor sites present in the body.

Out of the two kinds of Masteron that are available, the Propionate version is more popular than the Enanthate version. Propionate here refers to Propoinic acid.

Dromostanolone Propionate (known by the brand names Masteron and Drolban) was invented by Syntex in 1959. About 10 years later it was released on the American market by Lilly as brand name Drolban. The drug was first approved in the USA for use as a treatment of female breast cancer. However, the profile of side-effects included pronouncement of male characteristics in women and when more effective breast cancer treatments came to market drostanolone was gradually phased out. No longer used clinically dromostanolone propionate became very popular in the bodybuilding community. Today dromostanolone propionate remains on the list of approved medications, but it is not being manufactured or sold by pharmaceutical companies. It is still produced illegally by underground labs for use in the bodybuilding community.

One of the first few anabolic steroids to really hit the "mainstream", Masteron was first produced in 1959. A chemical laboratory called Syntex was responsible for cooking up this combination of chemical agents in 1959, working to produce a handful of different anabolic steroids that included Anadrol and Superdrol as well. Things really started to take off when the US Food and Drug Administration approved its use for medicinal purposes in the 1960s. The first medical prescriptions of Masteron were handed out as a treatment agent for women that were dealing with advanced and inoperable breast-cancer issues. This became the "standard operating procedure" for Masteron medicinal prescriptions around the world.

Of course, plenty of athletes and bodybuilders throughout the 1960s, 1970s, and especially in the 1980s took advantage of everything Masteron had to offer as far as lean muscle mass production and anabolic steroid results were concerned. Facing pushback from the US government because of how frequently these drugs were used in recreational settings by athletes, a number of manufacturers responsible for producing the Masteron formula voluntarily began discontinuing the sale of this chemical agent. During the late 1980s almost all production of Masteron ceased to exist, and the last few laboratories producing these chemical agents in the Western world were located in Belgium - and they shut their doors for good in the late 1990s. Though there are no laws or legal roadblocks stopping anyone from firing up production of Masteron again in the United States right now (this very minute), any widescale reemergence of Masteron as a prescription drug is considered to be very unlikely.

CaymanChem PDF Drostanolone

Drostanolone was never marketed. Drostanolone Propionate, was formerly used in the treatment of breast cancer in women under brand name Masteron. This ester has also been used non-medically for physique or performance enhancing purposes. Drostanolone and its ester drostanolone propionate were first described in 1959. Drostanolone Enanthate is strictly an underground anabolic androgenic steroid that is based on the discontinued Drostanolone Propionate compound known as Masteron.

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