DIHYDROTESTOSTERONE

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Created May 2019 | Updated Nov 2020

DIHYDROTESTOSTERONE

  • [DHT]
  • [ANDRACTIM]
  • [PESOMAX]
  • [STANOLONE]
  • [ANDROSTANOLONE]

(17BETA-HYDROXYANDROSTAN-3-ONE)

DEA CODE 4000: Schedule 3

STANOLONE, also known as dihydrotestosterone, is a potent androgenic metabolite of testosterone and anabolic agent for systemic use. It may be used as a replacement of male sex steroids in men who have androgen deficiency, for example as a result of the loss of both testes, and also the treatment of certain rare forms of aplastic anemia which are or may be responsive to anabolic androgens.

Dihydrotestosterone is a hormone with powerful androgenic actions, causes the body to mature during puberty and is responsible for many of the physical characteristics associated with adult males. It stimulates the development of male characteristics (an androgen). It is made through conversion of the more commonly known androgen, testosterone. Almost 10% of the testosterone produced by an adult each day is converted to dihydrotestosterone, by the testes and prostate (in men), the ovaries (in women), the skin and other parts of the body. This figure is much lower before puberty however, and it is thought that the increased dihydrotestosterone production may be responsible for the start of puberty in boys, causing development of the genitals (penis, testes and scrotum) and growth of pubic and body hair.

This hormone also causes the prostate to grow and is thought to combine with testosterone causing the expression of male sexual behaviour. Dihydrotestosterone is many times more potent than testosterone, and many of the effects that testosterone has in the body only happen after it is converted to dihydrotestosterone. Less is known about the importance of dihydrotestosterone in women, but it is known to cause much of the body and pubic hair growth seen in girls after puberty and may help to determine the age at which girls begin puberty.

The amount of dihydrotestosterone present in the body from day to day depends on the amount of testosterone present. When levels of testosterone increase, more of it is converted to dihydrotestosterone and so levels of dihydrotestosterone therefore also increase as a result. Control of dihydrotestosterone levels in the body is therefore achieved through control of testosterone production, which is controlled by the hypothalamus and the pituitary gland.

Male Pattern Baldness
Your chances of keeping your hair hinge on how sensitive you are to something called Dihydrotestosterone (DHT). One of the popular myths about balding is that it's a sign you have more testosterone than other guys. Strictly speaking, that's not correct. You can have as much testosterone as '80s Arnold Schwarzenegger, but what really matters is how much of it converts to DHT. It is a modified, more active form of testosterone. In your body, testosterone is transformed into DHT, which exerts stronger effects than testosterone itself. In fact, DHT is estimated to be five times more potent than the regular stuff. So even if you're a low-testosterone kind of guy, if your body is converting it heavily, you're in trouble.

DHT isn't all bad. In fact, without it we wouldn't be men in the first place. DHT helps develop our genitals in utero - meaning it makes us boys in the first place. It's a "sex steroid," so it also does the heavy work during puberty, lowering our voices and putting hair on our chests.

As hair on the scalp goes through its normal cycle of growing and shedding, DHT makes the follicles miniaturize. That means they get thinner - and shorter, because the growing cycle doesn't last as long. In some cases, the growing cycle becomes so brief that new hairs don't even poke through the skin. Plus, the thinning of the hairs makes them easier to shed. The result is classic "male pattern" baldness, the kind of balding that produces what the American Hair Loss Association calls a "horseshoe" shape, with hair growing from the temples and around the back of the head.

In some of our bodies, head hair and DHT co-exist in peace. But others of us are born with a genetic sensitivity to this particular sex steroid. A 2017 study from the University of Edinburgh identified 287 genetic regions that contribute to male pattern baldness. There's still much more work to be done to link which genes are interacting with DHT in what ways.

Hair loss is due to the shrinkage of hair follicles and the resulting impact on the growth cycle. New hairs become finer and finer until there's no hair left at all and the follicles become dormant. This hair loss is caused by hormones and certain genes. DHT is primarily used by the body in the prostate, skin, and hair follicles.

Male pattern baldness (MPB) has a distinctive shape. The front hairline recedes, especially at the sides, forming an M shape. This is frontal baldness. The crown of the head, also known as the vertex, becomes bald as well. Eventually the two areas join into a "U" shape. MPB can even extend to chest hair, which can thin as you age. Oddly enough, hair in different locations on the body can react differently to hormonal changes. For instance, facial hair growth can improve while other areas become bald.

It's not the amount of testosterone or DHT that causes baldness; it's the sensitivity of your hair follicles. That sensitivity is determined by genetics.

Women experience a different pattern of hair loss. Thinning occurs over the top of the scalp in a "Christmas tree" pattern, but the front hairline doesn't recede. Female pattern hair loss (FPHL) is also due to the actions of DHT on hair follicles.



Synthetic Dihydrotestosterone:

Andractim is Topical Dihydrotestosterone
Although Andractim DHT is much more potent than testosterone, in terms of both anabolic and androgenic effects, it has several possible nasty side effects, and several problems inherent with the form of administration (topical) as well as a couple of possible advantages due to those same factors. Pure Andractim DHT is a very poor choice for anabolism of any sort. I know we can all look at the anabolic/androgenic rating of it and say that its a very good anabolic steroid, but in actuality, what happens to DHT in the body is far different than what we would want. Your body reduces DHT to inactive metabolites before a lot of it can reach the androgen receptors in skeletal tissue.

Pesomax is an injectable form of dihydrotestosterone
Pesomax is very popular with European athletes, but is seldom available in the U.S. Bodybuilders like Pesomax for contest preparation. Pesomax reportedly promotes muscle growth and lipolysis. Its effectiveness holds good even on low calorie diets. Pesomax is not a steroid for gaining substantial strength of weight. The bodybuilders who are using this drug are obtaining it from European sources or from Canada it seems.

Stanolone or androstanolone is the powder form of dihydrotestosterone
For a fast buildup of power and muscle mass Androstanolone is of little value. Androstanolone used to be the athlete's favorite competition steroid since it helped to obtain a harder muscle through a lower fat content by increasing the androgen level without aromatizing. Today, however, Androstanolone is rarely used by athletes. One reason for this is that almost all European and American compounds are no longer commercially available. The other reason is that most athletes use the still readily available Masteron which has similar effects. Neither the original nor a fake of Androstanolone is available on the black market.

BFARM PDF Androstanolone

CaymanChem PDF Dihydrotestosterone

Androstanolone:
  • AKA dihydrotestosterone (DHT)
  • An androgen and anabolic steroid
  • Used mainly in the treatment of low testosterone levels in men
  • Also used to treat breast development and small penis in males
  • It is typically given as a gel for application to the skin, but can also be used as an ester by injection into muscle
  • Side effects of androstanolone include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire
  • Discovered in 1935
  • Introduced for medical use in 1953
  • It is used mostly in France and Belgium
  • It has been used by weightlifters to increase performance due to its powerful androgenic properties

  
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