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Created Jan 2021




DEA CODE 4000: Schedule 3

Prostanozol (demethylstanozolol THP) is an oral anabolic steroid closely related to Winstrol (stanozolol) in structure. It differs from stanozolol only by the removal of the c-17 alpha alkyl group, which undoubtedly hurts the oral bioavailability of this steroid. In an attempt to compensate for this, an ether group has been added. The ether increases oil solubility and the likelihood of lymphatic delivery with dietary fats, which bypass the first pass through the liver. This is the same principle on- which Anabolicum Vister (quinbolone) was developed. In the case of Prostanozol, however, there is no oil carrier, which significantly lowers the chance for lymphatic delivery.This will necessitate a much higher oral dosage than would be needed otherwise. Among athletes, the drug is valued as,a non-liver-toxic oral anabolic with properties qualitatively (although not quantitatively) similar to those of stanozolol.

Prostanozol History:
Demethylstanozolol appears to be a new chemical entity. If a non-methylated stanozolol were synthesized and assayed in the past, it could not be located.This steroid was introduced to the U.S. sports nutrition market in 2005 as a "post-ban" hormone, distributed openly as a "dietary supplement" instead of being regulated as a prescription drug. This is stemming from the fact that it was unknown to lawmakers at the time the 1991 and 2004 anabolic steroid laws were enacted, and as such simply could not be included in them. Although its legal status as a nutritional supplement may be in question (it is technically not found in the food supply, and therefore not a dietary food supplement), there are no U.S. criminal laws against its possession or use (yet).

Prostanozol is one of several legitimate synthetic anabolic/androgenic steroid products that hit the market in 2005. Later that year, however, the FDA and others in the government angrily acknowledged that there were new "designer steroids" on the supplement market, and made clear their intentions on investigating and even prosecuting those misbranding steroid products (drugs) as supplements.

Prostanozol belongs to a group of anabolic steroids developed to treat deficiency of male hormone testosterone in men and women. This steroid, also known as demethylstanozolol tetrahydropyran, is a modified form of dihydrotestosterone (biologically active form of hormone testosterone). In 2005, Prostanozol first appeared as a dietary supplement, rather than pharmaceutical drug on the US market. This steroid was in free sale, since it was developed already after adoption of steroid legislation (in 2004). Later Prostanozol was referred to "designer steroids". Principles of its prescription and sale have been revised. Prostanozol is a powerful oral steroid, so it has a status of prohibited drug for athletes during competitions.

Prostanozol, a.k.a. Demethylstanozolol Tetrahydropyranyl, is a modified version of dihydrotestosterone (DHT), an anabolic steroid that was designed as a male testosterone deficiency therapy drug. Prostanozol is structurally identical (with one exception) to Winstrol (Stanozolol) - the well known and definition promoting compound. The only difference between the two is the removal of Winstrols c-17 alpha alkyl (17aa) group - the component that grants it safe liver passage. Prostanozol replaces the 17aa group with an ether group (attached to the 17-beta hydroxyl group), for which oil solubility, via the lymphatic system, serves as the delivery method.

Steroid Form:
Prostanozol was marketed in the US (by its actual name) as a sports nutrition supplement, and when produced came in the form of a 25 mg oral capsule, but its no longer being manufactured.

2007 World Anti-Doping Agency:
The International Association of Athletics Federations has banned Russian runner Lyubov Denisova from competition for two years after she failed a doping test. Denisova, a two-time Los Angeles Marathon winner who set a course record at the Honolulu Marathon in December, tested positive for prostanozol and testosterone in a March 20 sample collected out-of-competition, the IAAF said.

Denisova's agent Andrey Baranov contends that the runner, who moved to Gainesville, Florida, from Moscow in January, made a mistake while buying vitamins on the Internet with her new computer early this year. Along with the vitamins, the 35-year-old athlete also bought Orasten-E, which is banned by the World Anti-Doping Agency.

It was found in 2005 as an ingredient of products sold as "dietary supplements" for bodybuilding.

It is one of hundreds of drugs banned from the Olympics. Russian marathon runner Lyubov Denisova was banned for two years from competition after testing positive for prostanozol and testosterone in 2007.

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