- Everything we could find out about it

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Created Oct 2019 | Updated Nov 2020


  • [ICE]
  • [CRANK]
  • [SPEED]

DEA CODE 1105: Schedule 2



Methamphetamine is usually a white, bitter-tasting powder or a pill. Crystal methamphetamine looks like glass fragments or shiny, bluish-white rocks. Methamphetamine is a stimulant drug that is chemically similar to amphetamine (a drug used to treat ADHD and narcolepsy). People can take methamphetamine by inhaling/smoking, swallowing, snorting, or injecting the drug. Methamphetamine increases the amount of dopamine in the brain, which is involved in movement, motivation, and reinforcement of rewarding behaviors. Short-term health effects include increased wakefulness and physical activity, decreased appetite, and increased blood pressure and body temperature. Long-term health effects include risk of contracting HIV and hepatitis; severe dental problems ("meth mouth"); intense itching, leading to skin sores from scratching; violent behavior; and paranoia.

Researchers don't yet know whether people breathing in secondhand methamphetamine smoke can get high or have other health effects. A person can overdose on methamphetamine. Because methamphetamine overdose often leads to a stroke, heart attack, or organ problems, first responders and emergency room doctors try to treat the overdose by treating these conditions. Methamphetamine is highly addictive. When people stop taking it, withdrawal symptoms can include anxiety, fatigue, severe depression, psychosis, and intense drug cravings. The most effective treatments for methamphetamine addiction so far are behavioral therapies. There are currently no government-approved medications to treat methamphetamine addiction.

The FDA-approved brand-name medication is Desoxyn.

Mexican drug trafficking organizations have become the primary manufacturers and distributors of methamphetamine to cities throughout the United States, including in Hawaii. Domestic clandestine laboratory operators also produce and distribute meth but usually on a smaller scale.

Meth is a highly addictive drug with potent central nervous system (CNS) stimulant properties. Those who smoke or inject it report a brief, intense sensation, or rush. Oral ingestion or snorting produces a long-lasting high in-stead of a rush, which reportedly can continue for as long as half a day. Both the rush and the high are believed to result from the release of very high levels of the neurotransmitter dopamine into areas of the brain that regulate feelings of pleasure. Long-term meth use results in many damaging effects, including addiction. Chronic meth users can exhibit violent behavior, anxiety, confusion, insomnia, and psychotic features including paranoia, aggression, visual and auditory hallucinations, mood disturbances, and delusions - such as the sensation of insects creeping on or under the skin.

Researchers have reported that as much as 50 percent of the dopamine-producing cells in the brain can be damaged after prolonged exposure to relatively low levels of meth. Researchers also have found that serotonin-containing nerve cells may be damaged even more extensively.

It comes in clear crystal chunks or shiny blue-white rocks. Also called "ice" or "glass," it's a popular party drug. Usually, users smoke crystal meth with a small glass pipe, but they may also swallow it, snort it, or inject it into a vein.

Where Does It Come From?
Methamphetamine is a man-made stimulant that's been around for a long time. During World War II, soldiers were given meth to keep them awake. People have also taken the drug to lose weight and ease depression. Today, the only legal meth product is a tablet for treating obesity and attention deficit hyperactivity disorder (ADHD). It's rarely used and is available only by prescription. Crystal meth is made with the ingredient pseudoephedrine, which is found in many cold medicines. It helps ease congestion. Because it's used to make meth, the federal government closely regulates products with this ingredient. Most of the crystal meth used in this country comes from Mexican "superlabs." But there are many small labs in the U. S. Some are right in people's homes. Making meth is a dangerous process because of the chemicals involved. Along with being toxic, they can cause explosions.

Gained popularity in the 1980's:
Methamphetamine and amphetamine were commonly prescribed during the 1950s and 1960s for a range of medical conditions, including narcolepsy, depression, and obesity. People began using methamphetamine and amphetamine recreationally in the 1960s, along with many other drugs, although meth waned in popularity until the 1980s. It recently gained popularity after the synthesis of a smokeable form of crystallized methamphetamine (d-methamphetamine hydrochloride) or crystal meth.

Methamphetamines in World War II
During World War II, German pharmaceutical company Temmler marketed methamphetamine tablets as a nonprescription drug under the brand name Pervitin. Methamphetamine triggers a response in the body that's similar to adrenaline, heightening alertness and a willingness to take risks. Japanese, U.S., British and German military personnel are reported to have used the stimulant to enhance endurance and ward off fatigue on long campaigns. Kamikaze pilots received high doses of Pervitin before suicide flight missions. Japanese factory workers also used methamphetamine to work longer hours. The German army ordered front-line soldiers and fighter pilots to take military-issued stimulants that contained a combination of methamphetamine and cocaine.

Many individuals who use meth take the drug over a period of several days, staying perpetually high throughout this duration of time. This often ends up in the development of a tolerance; after taking the drug for a prolonged period of a time a person will require higher and higher doses to feel the same effects as before. The stimulant effects, along with the drug's affordability, can lead people to quickly become addicted. It may then become difficult to feel happy when attempting to stop taking meth, and withdrawal symptoms such as anxiety, insomnia, fatigue, and depression can occur when it wears off. The debilitation of withdrawal reinforces the behavior of abuse and likelihood of binging. After the reward system is dependent on the drug, the fear of withdrawal and cravings for meth often take over a person's life.

Meth's dopamine increase isn't naturally duplicable:
In lab experiments on animals, sex will cause dopamine levels to go from 100 to 200 units; cocaine will make the levels go to 350 units. But meth will take those levels all the way to 1,250 units [source: PBS]. The increase in dopamine caused by methamphetamine isn't naturally duplicable. In order to feel that sensation again, a user has to take another dose of meth. Over time, as with any addictive substance, the effects of the drug decrease as the user's tolerance grows, requiring more and more of the drug to reach similar highs.

Meth users can maintain their interest in mundane activities for great lengths of time. As a result, performance of repetitive tasks continues at a high level for hours and hours, when normally it might wane due to boredom. Assembly-line workers and others who perform the same physical motion over and over suddenly find their work to be invigorating and even fascinating when high on crystal meth. Where life once seemed dreary and methodical, meth users may find that the drug keeps them "tuned in" to their work, speeding up their thoughts as well as their perception of the passing of time.

How is it made
Without getting into an exact recipe, we'll look at how large-scale operations (which are more likely to use a methodical and exact approach to their production) make crystal meth.

If the ephedrine or pseudoephedrine isn't already in pure powder form, then it must be separated from the tablets of cold medicine that contain it. To do this, the cold medicine tablets are mixed with a solvent and the solution is then filtered and exposed to low temperatures to separate and remove the inert material of the tablet.

The pure pseudoephedrine is then mixed with red phosphorus and hydriodic acid.

The red phosphorus is then filtered out (and later reused), and the remaining acid is neutralized by adding a lye solution.

A substance is added that will bind to the meth, and the liquid meth is then drained out.

Hydrogen chloride gas is bubbled through the liquid meth, making it a crystalline hydrochloride salt.

This is poured through a filter cloth, and the meth that is left on the filter is then dried.

Once dry, the meth is "stepped on" (mixed down with inert filler in order to maximize profits), weighed and packaged for shipment or sale.

This process generally takes about two days' time and can result in hundreds of thousands of methamphetamine doses.

Short Rush - Long High:
The rush from methamphetamine and crystal meth is strong but short-lived. Meth, specifically when smoked or injected, delivers a strong and euphoric "rush" sensation that both comes and goes quickly, lasting anywhere from 5 to 30 minutes and is followed by a 6-12 hour high. To avoid the crash, users often take repeated doses in a "binge and crash" pattern that can extend over several days with no sleep.

Methamphetamine's Effects on the Brain:
Methamphetamine is a very strong psychomotor stimulant that mimics the actions of certain neurotransmitters that affect mood and movement. Methamphetamine causes a release of dopamine and serotonin, producing the intense rush that users feel. Even after the initial rush subsides, the brain remains in an alert state and keeps the user's body on edge. After the effects have worn off, the brain is depleted of its dopamine, and depression is a common result. Methamphetamine easily hooks users because the highs are so intense and the lows are so awful. In addition, regular users build up a tolerance to the drug's effects, needing more of the drug to feel the original effect. Furthermore, methamphetamine can be extremely addictive. Methamphetamine appears to have neurotoxic (brain-damaging) effects, destroying brain cells that contain dopamine and serotonin. Over time, abuse appears to cause reduced levels of dopamine, which can result in symptoms like those of Parkinson's disease. Methamphetamine also stimulates locomotor activity (i.e. - reflexes, basic physical movements) and produces "stereotypic behaviors" - random, repetitive, compulsive movements and actions such as twitching or picking at the skin - as a side effect.

Methamphetamine Changes the Brain:
Usually neurons recycle dopamine. But Methamphetamine is able to fool neurons into taking it up just like they would dopamine. Once inside a neuron, Methamphetamine causes that neuron to release lots of dopamine. All this dopamine causes the person to feel an extra sense of pleasure that can last all day. But eventually these pleasurable effects stop. They are followed by unpleasant feelings called a "crash" that often lead a person to use more of the drug. If a person continues to use Methamphetamine, they will have a difficult time feeling pleasure from anything. Imagine no longer enjoying your favorite food or an afternoon with your friends.

Changes in Physical Appearance of People Who Are on Meth:
Methamphetamine is a disturbing, dangerous and highly addictive drug, and in many ways, it's one of the easiest to tell someone is using. Some of the most common signs of meth use tend to show up in their outer appearance. Crystal meth can have a dramatic and often terrifying impact on the user's looks, and give them certain distinctive characteristics that can show even a passerby they are on meth. First, people who are long-term users of meth will lose weight, and often significant amounts. Also, there is something called meth mouth. This is one of the top signs of someone on meth, and it indicates they have extreme tooth decay and tooth loss. The dental problems people on meth experience are thought to be from inadequate nutrition and hygiene, as well as dry mouth caused by the drug, and teeth grinding that occurs when someone is on meth. Another sign of someone on meth are skin sores. Skin sores tend to appear because the addict imagines they have insects crawling on their skin, and they will pick at them habitually, leading to the sores.

Meth for weight loss?
Females often take crystal meth because it can cause extremely rapid weight loss. However, the effects are short term. The body builds up a tolerance to the drug so weight loss tapers off and stops around six weeks after taking the drug. Also, the weight that is lost is regained once a person stops taking methamphetamine. For these reasons, combined with how addictive the drug is, methamphetamine tends not to be prescribed by doctors for weight loss.

Tooth decay:
Methamphetamine abuse can also cause tooth decay so severe that most of the teeth either rot, known as "meth mouth," or need extracting. Causes are thought to include:

  • having a dry mouth
  • increased consumption of sugary drinks
  • teeth clenching and grinding
  • a lack of dental hygiene

Meth Mouth:
Rampant tooth decay is another common side effect. Some users describe their teeth as "black-ened, stained, rotting, crumbling or falling apart."This condition often is called "meth mouth." Often,there is no hope of treating the methamphetamine damaged teeth, and they are extracted. The causes of methamphetamine related tooth decay may include the following:

  • the drug's acidic nature;
  • its ability to dry the mouth, reducing the amount of protective saliva around the teeth;
  • a drug-induced craving for high-calorie carbonated beverages;
  • the tendency of users to grind and clench their teeth;
  • the duration of the drug's effects (12 hours versus one hour for cocaine), which leads to long periods when users are not likely to clean their teeth.

ADA PDF Methamphetamine

Pulmonary Hypertension and Methamphetamine Use:
Information from a new study suggests that methamphetamine (speed) use is associated with the occurrence of IPAH. In that study, individuals with IPAH were 10 times more likely to have used stimulants than individuals with PAH associated with other known risk factors. Interestingly, that risk figure was similar to one found in studies of individuals who developed PAH and had used appetite stimulants (also known as anorexigens). While these are not controlled studies, they do make medical professionals aware of a strong association between stimulant use and PAH. How the two are associated, however (in terms of exactly how a specific stimulant would cause or contribute to the development of PAH), remains unknown. In addition, we know that amphetamines are similar to diet pills like fenfluramine, which is most well known as one component of the once-popular anti-obesity drug known as Fen-Phen. Fen-Phen has since been withdrawn from the market because of a potential link between use of that drug and development of PH and heart valve problems.

5 Facts About Meth the Anti-Drug Ads Won't Show You:
Meth is terrifying. Everybody knows that. Even professional drug enthusiasts cross themselves and spit on the ground at the mention of its name, for it is unclean. Shocker - we discovered that meth sucks! But much like heroin, it might not suck in the exact shape and form that has been described to you by pop culture.

  1. Meth Friends Are Not Imaginary
  2. Meth Addiction Comes With Bonus Downsides
  3. Regulating Pseudoephedrine Didn't Even Keep Meth Out of the Supermarket
  4. Anti-Meth Stigma Can Make the Problem Worse
  5. Most Meth Addicts Don't Look Like Meth Addicts

Everything You've Heard About Crack And Meth Is Wrong:
Growing familiarity with marijuana has been accompanied by growing support for legalization because people discovered through personal experience that the government was lying to them about the drug's hazards. But it is easier to demonize less popular drugs such as crack cocaine and methamphetamine, which in the public mind are still linked, as marijuana once was, with addiction, madness, and violence. Any attempt to question the use of force in dealing with these drugs therefore must begin by separating reality from horror stories.

Not instantly addictive for most:
Contrary to a common misperception, methamphetamine is not "instantly addictive" for most people who use it. Most people who use methamphetamine do not develop an addiction. For those individuals who do develop an addiction, treatment for methamphetamine addiction is similar to that for cocaine and other stimulants and just as likely to succeed.

Use is not on the rise:
Nationally, methamphetamine use is not on the rise, though there are regional differences. The number of Americans who report binge drinking in the last month - an indicator heavily associated with crime, violence and family dissolution - is more than 90 times the number who report using methamphetamine in the same period.

Less than one quarter of one percent of the population:
The proportion of Americans who use methamphetamine on a monthly basis has hovered in the range of 0.2 percent to 0.3 percent since 1999. Almost 11 million Americans have tried methamphetamine at least once - far fewer than those who have tried inhalants (23 million), psychedelics (34 million), cocaine (34 million), or marijuana (100 million). Of those 10.3 million, only 1.3 million used methamphetamine in the last year; and only 512,000 used it within the last 30 days. The estimated number of semi-regular methamphetamine users in the U.S. (those who use once a month or more) equals less than one quarter of one percent of the population (0.2 percent).

Meth is an incredible medicine:
In low, pharmaceutical - grade doses, methamphetamine may actually repair and protect the brain in certain circumstances. But stigma against the drug could be harming patients and holding back research. Ask your doctor about methamphetamine. It's not a phrase you'll ever hear on TV or the radio, but here's a secret: Meth is an incredible medicine. Even the Drug Enforcement Administration admits it, and doctors are known to prescribe it for narcolepsy, obesity, and ADHD. Historically, meth has been used to reverse barbiturate overdoses and even raise blood pressure during surgery. Some preliminary research suggests that meth can be neuroprotective against stroke and traumatic brain injury, even stimulating the growth of brain cells. Yet we're constantly warned never to try meth - "not even once," goes the refrain - or it will instantly cause addiction and ruin your life. Before fentanyl was the demon drug du jour, meth was seen as the worst, most destructive, most evil chemical you could find on the streets. Street doses of meth can be extremely damaging to your health. The purity of such drugs is often unknown, and repeated, high doses of meth have been proven to be neurotoxic. But in low, pharmaceutical-grade doses, meth may actually repair and protect the brain in certain circumstances.

Everything will kill you, if you take enough of it," Poulsen says. "Some things don't require a lot to do that. Meth is one of those things. But just like any drug, the difference between a poison and a cure is the dose.

Women use meth too:
Meth lures people looking for a high. But it also appeals to women trying to lose weight. Or those seeking a burst of energy to make it through the day. In fact, women use meth at rates that are about equal to men. That is unlike many other illegal drugs, which are mainly used by men. Meth use by women of child bearing age is of special concern. Children exposed to meth during pregnancy can have problems with brain development. These problems can cause attention deficits and behavioral problems as the children grow. Knowing that a child has been exposed to meth is critical. This can help prevent the emotional and behavioral problems from getting worse. When meth starts to wear off, abusers face 2 choices. They can suffer through what can be a 3-day bottoming-out period. That may include feeling grouchy, lacking energy, and having headaches. Or they can take another dose to ease their suffering. But they then risk addiction. More and more people are taking that second dose. People hear the myths that the drug does good things and lasts 12 hours a dose. They feel they can work longer hours, study more, and lose weight. Meth can also be easily found. Unlike other stimulants, it can be made in the kitchen sink using cheap household ingredients. But the process can be dangerous. Explosions are possible.


Summary of Use During Lactation:
Because there is no published experience with methamphetamine as a therapeutic agent during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Methamphetamine should not be used as a recreational drug by nursing mothers because it may impair their judgment and child care abilities.

Methamphetamine and its metabolite, (Narcolepsy) Amphetamine, are detectable in breastmilk and infant's serum after abuse of methamphetamine by nursing mothers. However, these data are from random collections rather than controlled studies because of ethical considerations in administering recreational methamphetamine to nursing mothers. Other factors to consider are the possibility of positive urine tests in breastfed infants which might have legal implications, and the possibility of other harmful contaminants in street drugs.

In mothers who abuse methamphetamine while nursing, withholding breastfeeding for 48 to 100 hours after the maternal use been recommended, although in many mothers methamphetamine is undetectable in breastmilk after an average of 72 hours from the last use. Nevertheless, breastfeeding is generally discouraged in mothers who are actively abusing amphetamines.

One expert recommends that amphetamines not be used therapeutically in nursing mothers.

Alternate Drugs to Consider:

Could methamphetamine use cause other pregnancy complications?
Yes. Methamphetamine abuse has been associated with a greater chance for premature delivery (delivery before 37 weeks of pregnancy), poor growth (babies born too small and/or with a small head size), and low birth weight. Some, but not all studies, have also suggested that methamphetamine abuse in pregnancy can increase the chance for high blood pressure, placental abruption (the placenta pulls away from the uterus) and for sudden infant death syndrome (SIDS). Pregnancy complications are more likely to occur when methamphetamine is misused throughout a pregnancy or when taken at high doses

Can I use methamphetamine while I breastfeed?
Methamphetamine should not be abused while breastfeeding. Methamphetamine can pass into breast milk. Methamphetamine has been detected in the blood and urine of breastfeeding babies.

Mothertobaby PDF Methamphetamine

Is it dangerous?
Yes. Methamphetamine causes the heart to beat faster and blood pressure to rise. Since what is sold as methamphetamine varies widely in terms of content and purity, users can't know how much they are taking. An overdose of methamphetamine can result in seizures, high body temperature, irregular heartbeat, heart attack, stroke and death. The risk of overdose is highest when the drug is injected.

Can you overdose or die if you use methamphetamine?
Yes, it is possible. Methamphetamine can raise your body temperature so much that you pass out. If not treated right away, this can cause death. Death can also occur from heart attack or stroke because the drug raises your heart beat and blood pressure, and constricts blood vessels. Nationwide, overdose deaths from the category of drugs that includes methamphetamine increased by 7.5 times between 2007 and 2017.1 In recent years, drug dealers have been secretly adding the deadly opioid fentanyl to methamphetamine, because it is cheaper to make. It is estimated that half of the deaths from meth use also involved a dangerous opioid like fentanyl.

Home Care: If you believe someone has taken methamphetamine and they are having bad symptoms, get them medical help right away. Take extreme caution around them, especially if they appear to be extremely excited or paranoid. If they are having a seizure, gently hold the back of their head to prevent injury. If possible, turn their head to the side in case they vomit. DO NOT try to stop their arms and legs from shaking.
Before Calling Emergency: Before you call for emergency help, have this information ready, if possible:

  • Person's approximate age and weight
  • How much of the drug was taken?
  • How was the drug taken? (For example, was it smoked or snorted?)
  • How long has it been since the person took the drug?
If the patient is actively having a seizure, becoming violent, or having difficulty breathing, do not delay. Call your local emergency number (such as 911).

How Long Does Methamphetamine Stay in Your System?
The substance remains present in urine for anywhere from four days to a week after use; and in the blood for up to 24 to 48 hours afterwards. Methamphetamine can be found in the hair for up to 90 days or longer after use.

Meth Is Making a Worrisome Comeback:
The rate of overdose deaths involving the stimulant more than tripled from 2011 to 2016, the Centers for Disease Control and Prevention reported. But unlike the opioid epidemic - for which medications exist to help combat addiction - medical providers have few such tools to help methamphetamine users survive and recover. A drug such as naloxone, which can reverse an opioid overdose, does not exist for meth. And there are no drugs approved by the Food and Drug Administration that can treat a meth addiction. "We're realizing that we don't have everything we might wish we had to address these different kinds of drugs," said Dr. Margaret Jarvis, a psychiatrist and distinguished fellow for the American Society of Addiction Medicine. The Drug Enforcement Administration reported that the price of meth is the lowest the agency has seen in years. It is increasingly available in the eastern region of the United States. Primary suppliers are Mexican drug cartels. And the meth on the streets is now more than 90 percent pure. "The new methods [of making methamphetamine] have really altered the potency," said Jane Maxwell, research professor at the University of Texas at Austin's social work school. "So, the meth we're looking at today is much more potent than it was 10 years ago."

Methamphetamine Use Report 2006:
inexpensive, easily made and in demand, methamphetamine is used by housewives, students, club-goers, truckers and a growing number of others. It is a drug with wide appeal. Some users are interested in its ability to make them more alert; others with its appetite suppressant effects; others with its ability to lift depression and/or make them more confident and energized for extended periods of time. This is not, however, a benign substance. Methamphetamine produces serious health risks to users, including cardiac and respiratory problems and extended or even perhaps permanent changes to the brain.

NCJRS PDF Methamphetamine

Seizures of meth in Thailand

Street Names for Methamphetamine:
METH: Beannies, Brown, Chalk, Crank, Chicken feed, Cinnamon, Crink, Crypto, Fast, Getgo, Methlies Quik, Mexican crack, Pervitin (Czech Republic), Redneck cocaine, Speed, Tick tick, Tweak, Wash, Yaba (Southeast Asia), Yellow powder
CRYSTAL METH: Batu, Blade, Cristy, Crystal, Crystal glass, Glass, Hot ice, Ice, Quartz, Shabu, Shards, Stove top, Tina, Ventana


A fairly common and very strong CNS stimulant. It is sometimes prescribed in the form of desoxyn for ADHD and severe obesity. In low doses, methamphetamine can elevate mood, increase alertness, concentration, energy and reduces appetite. At higher doses, it can induce mania, psychosis and muscle degeneration among other issues. Tolerant users may report much higher doses than new users.

RouteOnsetDurationAfter Effects
Tripsit Factsheets
IV:0-2 minuteshours24 hours
Smoked:0-2 minutes3-8 hours24 hours
Insufflated:5-10 minutes8-10 hours24 hours
Oral:20-70 minutes10-12 hours24 hours
Methamphetamine Duration
Rinsing mouth with mouthwash high in alcohol due to drying effects; using sugar filled chewing gum; usage within 14 days of MAOI
increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness, fatal kidney disorder, possible brain damage liver damage.
Deep reddish orange - Dark reddish brown

Desoxyn (Methamphetamine)
Side Effects:
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
  • signs of heart problems - chest pain, trouble breathing, feeling like you might pass out
  • signs of psychosis - hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia
  • signs of circulation problems - numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes
  • a seizure (convulsions)
  • muscle twitches (tics)
  • changes in your vision
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Methamphetamine can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.
Common side effects may include:
  • headache or dizziness
  • fast heartbeats
  • sleep problems (insomnia)
  • diarrhea, constipation, upset stomach
  • tremors
  • loss of appetite, weight loss
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Desoxyn is Prescribed for:
    What Conditions does it Treat?
  • Attention Deficit Disorder with Hyperactivity

This medication is used to treat attention deficit hyperactivity disorder - ADHD. It works by changing the amounts of certain natural substances in the brain. Methamphetamine belongs to a class of drugs known as stimulants.

It can help increase your ability to pay attention, stay focused on an activity, and control behavior problems. It may also help you to organize your tasks and improve listening skills.

This medication should not be used to treat tiredness or to hold off sleep in people who do not have a sleep disorder.

Before using:
Tell your doctor or pharmacist your medical history, especially of:

  • Blood circulation problems (such as Raynaud's disease)
  • High blood pressure
  • Diabetes
  • Glaucoma
  • Heart problems (including irregular heartbeat/rhythm, coronary artery disease, heart failure, cardiomyopathy, problems with the heart structure such as valve problems)
  • Mental/mood conditions (especially anxiety, tension, agitation)
  • Personal/family history of mental/mood disorders (such as bipolar disorder, depression, psychotic disorder, suicidal thoughts)
  • Personal or family history of a substance use disorder (such as overuse of or addiction to drugs/alcohol)
  • Personal or family history of uncontrolled muscle movements (such as motor tics, Tourette's syndrome)
  • Seizures
  • Stroke
  • Overactive thyroid (hyperthyroidism)


  • This drug may make you dizzy
  • Alcohol or marijuana (cannabis) can make you more dizzy
  • Do not drive, use machinery, or do anything that needs alertness until you can do it safely
  • Limit alcoholic beverages
  • Talk to your doctor if you are using marijuana (cannabis).

If you have diabetes, check your blood sugar regularly as directed and share the results with your doctor. Your doctor may need to adjust your diabetes medication during treatment with this drug.


Misuse or abuse of amphetamines may result in serious (possibly fatal) heart and blood pressure problems.

Amphetamine-type medications can be habit-forming. Use only as directed. If you use this drug for a long time, you may become dependent on it and may have withdrawal symptoms after stopping the drug. Consult your doctor or pharmacist for more details.

Read Reviews (35):

Before taking Desoxyn for ADHD:

Medical Problems:
Make sure you tell your doctor if you have any other medical problems, especially:

  • Agitation, severe
  • Anxiety, severe
  • Arteriosclerosis (hardening of the arteries), severe
  • Coronary artery disease
  • Drug abuse, history of
  • Glaucoma
  • Heart attack, recent
  • Heart failure
  • Heart or blood vessel disease (eg, cardiomyopathy)
  • Heart rhythm problem (eg, ventricular arrhythmia)
  • Hypertension (high blood pressure), severe
  • Hyperthyroidism (overactive thyroid)
  • Stroke, history of - Should not be used in patients with these conditions
  • Bipolar disorder (manic-depressive illness), or a family history of
  • Blood vessel problems (eg, Raynaud disease)
  • Depression, or a family history of
  • Hypertension (high blood pressure), mild
  • Psychosis (mental illness), history of
  • Seizures, history of
  • Tourette syndrome, or family history of - Use with caution. May make these conditions worse

Important information
You should not use methamphetamine if you have glaucoma, overactive thyroid, severe agitation, moderate to severe high blood pressure, heart disease or coronary artery disease, or a history of drug abuse.

Methamphetamine may be habit-forming, and this medicine is a drug of abuse. Tell your doctor if you have had problems with drug or alcohol abuse.

Stimulants have caused stroke, heart attack, and sudden death in people with high blood pressure, heart disease, or a heart defect.

Do not use methamphetamine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Methamphetamine may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have a history of depression, mental illness, or bipolar disorder.

You may have blood circulation problems that can cause numbness, pain, or discoloration in your fingers or toes.

Call your doctor right away if you have:

  • signs of heart problems - chest pain, feeling light-headed or short of breath;
  • signs of psychosis - paranoia, aggression, new behavior problems, seeing or hearing things that are not real;
  • signs of circulation problems - unexplained wounds on your fingers or toes.
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid drinking fruit juices or taking vitamin C at the same time you take methamphetamine. These can make your body absorb less of the medicine.

NDIC PDF Methamphetamine

SAMHSA PDF Methamphetamine

EPA PDF Methamphetamine

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Oregon to recriminalise drugs after ‘dystopian nightmare’ of fentanyl addiction - The US state of Oregon has voted to reverse the decriminalisation of drug possession, after experimental measures fuelled a “dystopian nightmare” of fentanyl addiction on the streets.
Friday March 01, 2024 -

Grand Forks man pleads guilty to drug conspiracy charge in Polk County - A Grand Forks man pleaded guilty to conspiracy to commit a first-degree controlled substance crime on Thursday, Feb. 29, in Polk County. Todd Jonas Hicks, 52, was arrested after another man — Conner ...
Saturday March 02, 2024 -

Weathersfield drug bust turns up 74g of suspected methamphetamine - WEATHERSFIELD — A raid conducted by the Trumbull Action Group Drug Task Force and other local agencies turned up approximately 74 grams of suspected methamphetamine from a township residence Tuesday.
Wednesday February 28, 2024 -

Oregon lawmakers pass bill to recriminalize drug possession - The measure makes the possession of small amounts of drugs such as heroin or methamphetamine a misdemeanor, punishable by up to six months in jail. SALEM, Ore. — A bill recriminalizing the possession ...
Friday March 01, 2024 -

Impending Reinstatement of Drug Possession Penalties in Oregon and Its Implications - Oregon may soon reverse its groundbreaking decriminalization of drug possession as the state Senate approves a new measure. The law, initially enacted in 2021, eliminated criminal penalties for ...
Saturday March 02, 2024 -

Ore. lawmakers reverse course on drug decriminalization amid fentanyl crisis - Related Fentanyl state of emergency declared for Portland Methamphetamine use propels drug overdoses in rural America, study finds CDC: Fentanyl-related overdose deaths rose nationally during pandemic ...
Saturday March 02, 2024 -

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