Dipipanone are indicated for the management of moderate to severe pain in medical and surgical conditions in which morphine may be indicated. Dipipanone is related to methadone and can be substituted for assorted opioids. The severe or irreversible adverse effects of Dipipanone, which give rise to further complications, include hypotension, hypotension, hependence, agranulocytosis, ischemic colitis, generalized chorea, hypersensitivity hepatitis. It may interact badly with monoamine oxidase inhibitors, which are substances found in some antidepressants and other medication.
Dipipanone and Cyclizine
Dipipanone is a type of medicine called an opioid painkiller. Dipipanone mimics the action of natural endorphins by combining with the opioid receptors in the brain and spinal cord. This blocks the transmission of pain signals sent by the nerves to the brain. Therefore, even though the cause of the pain may remain, less pain is actually felt. Nausea and vomiting are common side effects of opioids such as dipipanone and cyclizine is included in these tablets to combat these effects. Cyclizine is an anti-sickness medicine. Vomiting is controlled by an area of the brain called the vomiting centre. The vomiting centre is responsible for causing feelings of sickness (nausea) and for the vomiting reflex. Cyclizine prevents the vomiting centre from receiving messages from an area of the brain called the chemoreceptor trigger zone (CTZ). The CTZ is stimulated by agents circulating in the blood, for example opioid painkillers such as dipipanone. Cyclizine helps prevent these agents from activating the vomiting centre and causing sickness.
Dipipanone and cyclizine tablets can therefore be used to relieve moderate to severe pain associated with a variety of medical and surgical conditions, while also preventing nausea and vomiting from the dipipanone.
Dipipanone + Cyclizine: Otherwise known as Pinks, Inxs or Inkiltins. It contains dipipanone, which is a derivative of methadone and a potent analgesic (pain relieving) drug. It is a powerful synthetic narcotic and is medically prescribed for people who are terminally ill or experiencing severe pain.
An addict who survived pinks writes: I stumbled on your site and was intrigued to see the stuff about wellconal. In Liverpool known as Diconal. pink scored tabs marked f3a. There was an epidemic of dike use in the early 70's 'cause the effect was like a poor mans speedball. The cyclizine gave it the hallucinatory dimension. To this day I remember vividly the involuntary cough as I successfully mainlined 3 dike crushed and shook in suspension into my groin (femoral vein) the pause then the rush. They reduced the shelf life of veins to days rather than years. When we couldn't get them we discovered we could inject over the counter Marzine travel sickness tablets (just cyclizine) mixed with methadone amps to get nearly the same buzz. Practically everyone who used that way is long dead or disappeared.
It sometimes feels that like Melville's Ishmael I alone survived to tell the tale. Anyway, I found recovery through my wife in '88 went through treatment got clean and we're both 15 years clean now. I still marvel at it every day. Especially now as 2003 slips rapidly away. Thank you and best wishes to you and yours for the New Year Yours in fellowship. - Nick M. United Kingdom
Wellconal is a prescription painkiller. It contains dipipanone, which is a derivative of methadone and a potent analgesic (pain relieving) drug. It is classed as Narcotic Analgesic, along with Heroin, and is a Central Nervous System(CNS) depressant. It is prescribed when people are suffering extreme pain, such as terminal diseases like malignant cancers. It also contains cyclizine (3/4 by mass) to stop vomiting.
It comes in a pink, scored tablet, marked 'Wellcome' after the company that makes it. If taken orally, it produces a euphoric state. However if crushed and mixed with water and injected, a rush is experienced. Within seconds of being injected, it produces an overwhelming, inexplicable feeling. This last for a 20/40 seconds after which you subside into a euphoric bliss which gradually wears off over an hour or so. Auditory and visual hallucinations have also been reported. Physical and psychological dependency occurs rapidly, as well as tolerance. Addiction is almost inevitable. Not using for any period will result in loss of tolerance, and doses should be adjusted accordingly to prevent overdose.
Wellconal collapses veins extremely easily and users soon find themselves shooting deep veins such as the groin and throat. Poor nutrition, personal neglect, and polluting the body lead to poor health. Many Wellconal users die from an over dose. It is unusual for a user to live longer than the two to five years after becoming dependent. Users often slip into a coma and die even after having doses smaller than their usual. They often forget having had a shot directly after having it, and so they may have another and overdose. Because of this, Wellconal users should never use alone.
Diconal is the brand name of an opiate painkiller, dipipanone hydrochloride. It is a pink tablet which is sometimes prepared for injection by chronic users of heroin and similar drugs. Diconal tablets contain some ingredients (including the anti-nausea drug cyclizine) which, if injected intravenously, can cause local vein damage. Damage to veins puts the drug use at risk of developing abcesses.
A powerful opioid of equivalent strength to morphine, rarely seen outside of medical environments. Often used to treat severe pain where morphine is contraindicated. Usually found in combination with the antihistamine Cyclizine, which potentiates it.
|Intravenous:||0-1 minutes||3-6 hours||1-12 hours|
|Insufflated:||5-15 minutes||3-6 hours||1-12 hours|
|Oral:||15-30 minutes||3-6 hours||1-12 hours|
All other CNS depressants
Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.
If you do come across these pills, and IV them, you will reach a point where the Cyclizine in the Diconal preparation will reach a very bad result, and missed shots can end up with amputations.
Dipipanone is used for very severe pain in cases where other analgesics are unsuitable, for instance where morphine is indicated but cannot be used due to the patient being allergic to morphine. The main preparation of the drug commercially available is mixed with cyclizine (Diconal, Wellconal) which has the advantage of reducing nausea, vomiting and histamine release associated with strong opioid therapy.
With the exception of oxycodone, dipipanone is now the only alternative opioid left to use in the UK that is of equal strength to morphine that can be prescribed instead. All the other opioids are either weaker like codeine, dihydrocodeine and pethidine or stronger like hydromorphone, methadone, and fentanyl.
Dipipanone is now unavailable in most countries of the world either by laws prohibiting its medicinal use as in the United States or by falling out of production as more modern analgesics took its market share.
Drug death was ‘tragic accident’ - The wiring technician had taken a fatal dose of prescription drug dipipanone, which he had mixed with alcohol the previous evening. County coroner Dr Peter Dean said his death emphasised the ...
Tuesday November 01, 2011 - eadt.co.uk
|Opioids | Link to this page|