ANPP

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Created Apr 2019

ANPP

  • [DESPROPIONYL FENTANYL]

4-ANILINO-N-PHENETHYL-4-PIPERIDINE (ANPP)

DEA CODE 8333: Schedule 2

Tom Petty died from, according to the New York Times headline, an "Accidental Drug Overdose." Here's the coroner's list of the drugs found in Petty's system:
fentanyl, oxycodone, temazepam, alprazolam, citalopram, acetyl fentanyl and despropionyl fentanyl.

Petty's death is not accurately classified as an overdose. He died due to a dangerous mixture of opioid drugs. Such drug intake, often classified as "chaotic" drug use, is the source of over 90% of deaths involving drugs, so much so that the CDC now classifies these deaths as "drug poisonings" rather than as "overdoses."

"But what concerns me even more are the last two drugs: acetyl fentanyl and despropionyl fentanyl. These are nonprescription, synthetic opioid relatives of fentanyl that are not used medically. Despropionyl fentanyl is better known by its acronym, ANPP is more often seen as an illicit chemical precursor in the synthesis of other designer fentanyls and, according to Cayman Chemical, is sometimes found as an unreacted impurity in illicit fentanyl preparations. How Petty might have been exposed to these two compounds on top of the prescription opioids is concerning.

  
4-ANPP: Fentanyl in Waiting - 4-ANPP is not a term that most of you know but it's hugely important. It is the chemical that is the precursor to fentanyl. Although 4-ANPP is not an opioid, there is not a single thing anyone would ...
Monday January 09, 2023 - acsh.org

Making Synthetic Drugs: A Primer* - The process of making synthetic drugs involves various steps, but it must include a key ingredient called a precursor. For methamphetamine, these precursors are 1-phenyl-2-propanone (P2P) and ...
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What's Scarier: Fentanyl, or Fentanyl Made By Mexican Sophomores? - A recent article in The New York Times described how Mexican cartels were recruiting college students to "cook" fentanyl, to address shortages. But the students were having all sorts of problems ...
Tuesday December 03, 2024 - acsh.org

How Fentanyl Is Synthesized in Mexico - In 2018, US and Mexican authorities began tracking several chemists working for the Sinaloa Cartel in Mexico that were trying to synthesize fentanyl. The investigations included wiretaps in which ...
Monday May 08, 2023 - insightcrime.org

New Bern woman sentenced to 5 years on fentanyl related drug charges - The 37-year-old pleaded guilty to trafficking fentanyl by possession, possession of a controlled substance in the jail, possession of meth, and destroying evidence. Harrell received 5 to 8 years ...
Friday September 05, 2025 - msn.com

Three sentenced in Craven County for drug charges - Three Craven County residents were recently sentenced to prison terms for various drug crimes. District Attorney Matt Wareham made the announcement on Friday, September 5, that Alexandria Elaine ...
Friday September 05, 2025 - msn.com

  
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