ANPP

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Created Apr 2019

ANPP

  • [DESPROPIONYL FENTANYL]

4-ANILINO-N-PHENETHYL-4-PIPERIDINE (ANPP)

DEA CODE 8333: Schedule 2

Tom Petty died from, according to the New York Times headline, an "Accidental Drug Overdose." Here's the coroner's list of the drugs found in Petty's system:
fentanyl, oxycodone, temazepam, alprazolam, citalopram, acetyl fentanyl and despropionyl fentanyl.

Petty's death is not accurately classified as an overdose. He died due to a dangerous mixture of opioid drugs. Such drug intake, often classified as "chaotic" drug use, is the source of over 90% of deaths involving drugs, so much so that the CDC now classifies these deaths as "drug poisonings" rather than as "overdoses."

"But what concerns me even more are the last two drugs: acetyl fentanyl and despropionyl fentanyl. These are nonprescription, synthetic opioid relatives of fentanyl that are not used medically. Despropionyl fentanyl is better known by its acronym, ANPP is more often seen as an illicit chemical precursor in the synthesis of other designer fentanyls and, according to Cayman Chemical, is sometimes found as an unreacted impurity in illicit fentanyl preparations. How Petty might have been exposed to these two compounds on top of the prescription opioids is concerning.

  
4-ANPP: Fentanyl in Waiting - 4-ANPP is not a term that most of you know but it's hugely important. It is the chemical that is the precursor to fentanyl. Although 4-ANPP is not an opioid, there is not a single thing anyone would ...
Monday January 09, 2023 - acsh.org

The Real Reason for the Drop in Fentanyl Overdoses - Drug deaths are finally falling—but the cause may be far outside of U.S. policy makers’ control.
Tuesday January 20, 2026 - msn.com

Making Synthetic Drugs: A Primer* - The process of making synthetic drugs involves various steps, but it must include a key ingredient called a precursor. For methamphetamine, these precursors are 1-phenyl-2-propanone (P2P) and ...
Sunday May 07, 2023 - insightcrime.org

What's Scarier: Fentanyl, or Fentanyl Made By Mexican Sophomores? - A recent article in The New York Times described how Mexican cartels were recruiting college students to "cook" fentanyl, to address shortages. But the students were having all sorts of problems ...
Tuesday December 03, 2024 - acsh.org

How Fentanyl Is Synthesized in Mexico - In 2018, US and Mexican authorities began tracking several chemists working for the Sinaloa Cartel in Mexico that were trying to synthesize fentanyl. The investigations included wiretaps in which ...
Monday May 08, 2023 - insightcrime.org

  
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