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Created Jan 2020




DEA CODE 1635: Schedule 4

Lefetamine (L-SPA; L-1,2-diphenyl-l-dimethylaminoethane hydrochloride) is a synthetic compound with analgesic and anti-inflammatory action, introduced in clinical practice in Italy and Japan as 'Santenol'. Santenol is available for oral (50 mg tablets1 and intramuscular (60 mg vials containing also lidocainel use. Animal studies have shown an analgesic effect and changes in EEG activity and O2 consumption of the nervous tissue. Lefetamine may be an opioid partial agonist. Lefetamine was first marketed in the 1940s as an opioid analgesic. Since withdrawal symptoms were observed during treatment, it became a controlled substance.

A Bluelight Lefetamine Thread (2007):

  • After the Second World War, the Japanese public, desperate to rebuild their shattered economy & infrastructure went on one almighty binge to help them work. Amphetamines were cheaper than food and allowed the beaverlike Japanese to work even harder. The drug they went for wasn't (meth)amphetamine, ritalin or anything like. It was this. It is reported to have both stimulant & 'opiate like' effects everywhere I read. It produces opiate tolerance & dependance that naloxone precipitates withdrawal syndrome. It is usually described as a 'partial agonist'. So, stimulant AND opiate. Sounds like a speedball with one chemical, doesn't it.

A Reddit Lefetamine experience (37 comments):

  • Around 1230 I took 20 mg to make sure I wouldn't die or have a seizure and went to the store. Got home around 130 and didn't feel anything but I wasn't dead so I took 40 mg more. About 20 minutes later there was a definite codeine feeling, like a small warmth in the limbs. Another 20 minutes and my mind is stimulated, but my eyes feel droopy and I'm super relaxed. I pour myself some vodka and mountain dew and relax for an hour. The feeling subsides or is taken over by the alcohol an hour later. I take another 40 mg at around 3. The warm opiate feeling returns and is here as I type this. I'm very glad that I was able to make this drug with relative ease. I can see how it could be addictive, and I'm very curious to try a dose of 100 mg all at once. The stimulant side of it is way more in the brain, the body is warm and fuzzy but the brain goes 100 miles an hour for a few minutes at a time.
  • Back at baseline in about 4 hours. The stimulant effect is barely noticeable and only for about 30 minutes, the opiod effect is very nice and overpowering it. But there was none of the stimulant jitters I usually get, it was more mental than anything. Like a weak dose of Adderall for maybe an hour. Ill be taking 100 mg tomorrow so hopefully I can get some more of the stimulant effect.

Lefetamine is a diphenylethanamine with opiate-like effects. While it has limited potential in detoxification treatment of opiate and methadone addiction, lefetamine is widely abused.

CaymanChem PDF Lefetamine

  • A stimulant painkiller
  • Effects comparable to codeine.
  • Invented in the 1940s
  • It was abused in Japan during the 1950s
  • It has been abused in Europe
  • Some partial similarity to opioids

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Spa owner and employees among seven held in drug raid - "The woman and three others also tested positive for drugs," the source said on Thursday (Dec 29). It is learnt that the woman is the owner of a chain of spa and wellness centres in the Klang Valley.
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Patients needing home IV nutrition fear dangerous shortages - Pharmacy closures and layoffs by two large home infusion companies spark fears for those who require parenteral nutrition.
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Saratoga County unveils new tool for substance abuse surveillance - At a press conference at the Saratoga County Public Safety Building, county officials unveiled a new data collection tool that will allow near real-time monitoring of opioid ...
Tuesday February 07, 2023 -

Decisions by CVS and Optum Panicked Thousands of Their Sickest Patients - Pharmacy closures by two of the biggest home infusion companies point to grave shortages and dangers for patients who require IV nutrition to survive.
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Saratoga County Drug Overdoses on the Rise - A Public Health Advisory was issued Jan. 20 by the Saratoga County Department of Health reporting an increase in drug-related overdoses – 10 in all including one fatality – during a 7-day period ...
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FDA Issues Orphan Drug Exclusivity Policy That Could Be a Catalyst for Future Litigation - FDA published a notice in the Federal Register entitled, “Clarification of Orphan-Drug Exclusivity Following Catalyst Pharms., Inc. v. Becerra.”[1]  In ...
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Global Endocrine Therapy Drugs (ETDs) Market [2023-2028] | Stay Ahead of the Competition with Our Advanced Research Report | Latest Report - Market Provides Such by Type- Antidiabetic Drugs,Anti-osteoporosis Drugs,Contraceptive,Other, such by Application- Diabetes Treatment,Osteoporosis Treatment,Contraception,Other, Also Provide Key ...
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