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Created Jan 2021


DEA CODE 9732: Schedule 2 Narcotic

Racemethorphan is racemic mixture of Dextromethorphan and Levomethorphan. Racemethorphan is listed under the Single Convention on Narcotic Drugs 1961 and is therefore listed in the United States as a Controlled Substance, specifically as a Narcotic in Schedule II. Dextromethorphan is a non-narcotic morphine derivative widely used as an antitussive. Dextromethorphan is a cough suppressant in many over-the-counter cold and cough medicines. In 2010, the FDA approved the combination product dextromethorphan/quinidine for the treatment of pseudobulbar affect. Dextromethorphan suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. Levomethorphan is an opioid analgesic of the morphinan family that has never been marketed.

  • Methorphan comes in two isomeric forms, each with differing pharmacology and effects:

    1. Dextromethorphan - An over-the-counter cough suppressant, as well as dissociative hallucinogen.
    2. Levomethorphan - A potent opioid analgesic that was never clinically developed; the codeine analogue of the powerful opioid agonist analgesic levorphanol (Levo-Dromoran).

    Racemethorphan refers to the racemic mixture of both of these stereoisomers.

  • Annual aggregate manufacturing quota of 3 grams in 2014.

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