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PYROVALERONE
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- Pyrovalerone is a psychostimulant.
- It has a central action.
- Pyrovalerone inhibits the dopamine transporter and the norepinephrine transporter, and is a weak inhibitor of the serotonin transporter.
- Pyrovalerone was demonstrated to reduce symptoms of chronic fatigue in humans.
- It stimulated locomotor activity in mice.
- Though pyrovalerone is still occasionally prescribed, it is used infrequently due to problems with abuse and dependence.
- Side effects of pyrovalerone include anxiety, fragmented sleep or insomnia and trembling, shaking or muscle tremors.
Pyrovalerone:
https://drugs.ncats.io/drug/VOU69C02JP
https://www.reddit.com/search/?q=Pyrovalerone
- A psychoactive drug
- Stimulant effects
- Used for the clinical treatment of chronic fatigue or lethargy and as an anorectic or appetite suppressant for weight loss purposes
It was developed in the late 1960s and has since been used in France and several other European countries, and although pyrovalerone is still occasionally prescribed, it is used infrequently due to problems with abuse and dependence.
- It is closely related on a structural level to a number of other stimulants
- Side effects of pyrovalerone include anorexia or loss of appetite, anxiety, fragmented sleep or insomnia, and trembling, shaking, or muscle tremors.
Withdrawal following abuse upon discontinuation often results in depression
New Drug Described As More Powerful Than Cocaine - WLWT - The Drug Enforcement Administration said MDPV is a "designer drug" based upon a legal stimulant, pyrovalerone, which is used as an appetite suppressant or for the treatment of chronic fatigue. Thursday August 05, 2010 - wlwt.com What you need to know about 'bath salts' - Fox News - According to the National Institute on Drug Abuse (NIDA), bath salts typically contain amphetamine-like chemicals, such as methylenedioxypyrovalerone (MPDV), mephedrone and pyrovalerone. Sweetwater To Ban Bath Salts In Addition To Fake Marijuana - Sweetwater Mayor Manny Maroño plans to amend a city ordinance passed on May 21st to include bath salts due to a weekend incident in which Rudy Eugene, reportedly in a drug-fueled rage, took part ... Miami-Dade Commission Approves Bath Salt Ban - CBS Miami - The Drug Enforcement Agency groups bath salts with mescaline and ephedrine, while dealers market the drug as a replacement for cocaine or a synthetic form of the hallucinogen LSD, according to CNN. The war on drugs through regulation | Opinion - "For a couple of years now, the hands of local and state law enforcement were tied when it came to the deadly designer drugs known as 'bath salts,' " reported Reno's KOLO-TV on Feb. 17. 'Bath Salts' A Deadly New Drug With A Deceptively Innocent Name - The Lowdown on "Bath Salts": The new designer drug known as "Bath Salts" triggers hallucinations that may lead to extreme violence, such as the cannibalism of the "Miami Zombie" episode. Bath salts difficult to detect in biological samples, study finds - Synthetic cathinones or 'Bath salts' continue to be popular among recreational drug users and a new study highlights the challenges associated with the detection of these drugs in biological evidence. Ban mephedrone-like legal high, says UK drug advisor - It has a close chemical resemblance to cathinones such as mephedrone and pyrovalerone – a drug developed in the 1960s to treat fatigue but largely abandoned due to the risk of abuse and addiction. “Bath Salts” Intoxication | New England Journal of Medicine - References 1. Emergency department visits after use of a drug sold as “bath salts” -- Michigan, November 13, 2010-March 31, 2011. MMWR Morb Mortal Wkly Rep 2011;60:624-627 ...
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