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Created Sep 2019 | Updated Nov 2020



Brand names: Azepamid, Nobrium, Tranquirax (mixed with bevonium), Rudotel, Raporan, Ansilan, and Mezapam

DEA CODE 2836: Schedule 4


Benzodiazepine derivative that has all of the classic benzodiazepine effects. Is a long-acting benzodiazepine drug (Half life of 36-200 hours) Is rarely prescribed in most countries. Is also a prodrug for Diazepam. Think of it as Desoxy-Diazepam if you'd like to.

RouteOnsetDurationAfter Effects
Tripsit Factsheets
All ROAs:30-120 minutes8-16 hours1-172 hours
Medazepam Duration
All other CNS depressants.

Medazepam is a benzodiazepine drug with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Marketed in Russia. Indicated for the treatment of neurotic disorders and states, accompanied with sense of fear, anxiety, intension, raised irritability, insomnia, vegetative lability.

Detox Timeline:
The half-life of medazepam is estimated to be between 36 and 200 hours, making it an extremely long-acting benzodiazepine drug. Depending on the severity of a person's physical level of dependence on medazepam, withdrawal may range in intensity and duration. The more medazepam a person used, and for a longer time, the more dependent the brain likely is on it and the more difficult withdrawal may be. Detox generally adheres to the following timeline for medazepam:

  • First few days (likely between 2-4 days): Withdrawal symptoms may start, and sleep disturbances and other rebound symptoms are most common.
  • Between two days and a week: Acute withdrawal peaks, and symptoms are most severe.
  • One week to 14 days: Symptoms start to subside.
  • Up to several weeks: Lingering psychiatric symptoms may continue.

The half-life of a drug is the time it takes for it to be broken down in the body until it is half as effective. By doubling the half-life, one can get an indication of when the drug will be completely out of the system and no longer active.

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