JB 323

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Created Aug 2019

JB 323



DEA CODE 7482: Schedule 1

Pipenzolate bromide is a synthetic anti-muscarinic cholinergic antagonist, used for Gastro intestinal spasm, & Flatulent dyspepsia. Pipenzole methylbromide is used for flatulent dyspepsia, infantile colics and other gastrointestinal spasms.

This product is a tertiary amine antimuscarinic. It is similar to atropine. It is mainly used in the smooth muscle spasm of the gastrointestinal tract and inhibits intestinal cramp induced by acetylcholine in rats and dogs.

Pipenzolate bromide is an antimuscarinic. It binds to muscarinic acetylcholine receptors as an antagonist therefore preventing acetylcholine from binding to the receptors.

Muscarinic antagonists reduce the activation of the parasympathetic nervous system. The normal function of the parasympathetic system is often summarized as "rest-and-digest", and includes slowing of the heart, an increased rate of digestion, narrowing of the airways, promotion of urination, and sexual arousal. Muscarinic antagonists counter this parasympathetic "rest-and-digest" response, and also work elsewhere in both the central and peripheral nervous systems.

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