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Created May 2019 | Updated Oct 2020


  • [DET]


DEA CODE 7434: Schedule 1


A surprisingly uncommon analogue of DMT with similar effects and reported oral activity without the aid of an MAOI.

RouteOnsetDurationAfter Effects
Tripsit Factsheets
Oral:30-90 minutes2-4 hours1-6 hours
Vaporized:1-5 minutes2-4 hours1-6 hours
DET Duration
Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.

A synthetic psychedelic drug and a close structural analog of DMT (Dimethyltryptamine). Its activity is induced by an oral dose of around 50 - 100 mg, without the aid of MAO inhibitors, and the effects last for about 2 - 4 hours. DET is sometimes preferred over DMT because it can be taken orally, whereas DMT cannot. This is because the enzyme monoamine oxidase degrades DMT into an inactive compound before it is absorbed. To overcome this, it must be administered in a different manner, i.e. intravenously, intramuscularly, by inhalation, by insufflation, rectally, or ingested along with an inhibitor of monoamine oxidase. Because DET has ethyl groups attached to its nitrogen atom, monoamine oxidase is unable to degrade it. This is also true for many other tryptamines with larger nitrogen substituents.

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