Cannabinoid receptors are embedded in the cellular membrane in the central nervous and immune systems as well as in various organs. Both endocannabinoids and phytocannabinoids bind to these receptors or influence them indirectly. As external environments and stressors change, the Endocannabinoid System helps the body maintain a stable biological environment, or homeostasis.
There are two different types of cannabinoid receptors: CB1 and CB2. CB1 receptors are found primarily in the brain, and are responsible for the psychoactive effects of marijuana. On the other hand, CB2 receptors are found mostly in other parts of the body. They are responsible for a wide range of biological functions.
Endocannabinoids are cannabinoids that are produced naturally by the human body. While these cannabinoids are distinct from those produced in marijuana, they share many similar properties and effects. This is because they interact with the same pathways in the brain and body called cannabinoid receptors.